EINECS No. 418-680-6 Taxane Drugs 10-Deacetylbaccatin III 99.5% 10-DAB

EINECS No. 418-680-6 Taxane Drugs 10-Deacetylbaccatin III 99.5% 10-DAB

Chemical Name:
(2α,5β,7β,10α,13α)-4-Acetoxy-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
(2α,5β,7β,10β,13α)-4-(acetyloxy)-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate

Other Name:
10-Dab
10-DAB (10-Deacetylbaccatin)
10-Deacetylbaccatine
10-deacetylbaccatin11

10-Deacetyl Baccatin III or 10-DAB III is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever invented. By extracting the pre-cursor 10-DAB III in large quantites from the Taxus baccata leaf, many subsequent semi-syntheses can be carried out. The esterification of 10-DAB III also causes an enhancement in the kinetics, and therefore the pharmacological profile of these important chemo-therapeutic agents.

Storage:

It should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.