Cabazitaxel 99%TC CAS No. 183133-96-2 Taxane Drugs White or off white crystalline powder
Technical Item | Technical Data |
---|---|
Density |
1.3±0.1 g/cm3 |
Boiling Point |
870.7±65.0 ℃ at 760 mmHg |
Molecular Formula |
C45H57NO14 |
Formula Weight |
835.932 |
Flash Point |
480.4±34.3 ℃ |
Exact Mass |
835.377930 |
PSA |
202.45000 |
Log P |
7.55 |
Vapour Pressure |
0.0± 0.3 mmHg at 25℃ |
Refractive Index |
1.592 |
Residual Solvents
Acetone |
≤ 5000ppm |
Dichloromethane |
≤ 600ppm |
n-Hexane |
≤ 290ppm |
Acetic acid |
≤ 5000ppm |
Ethyl acetate |
≤ 5000ppm |
Tetrahydrofuran |
≤ 720ppm |
Ethanol |
≤ 5000ppm |
Function of Cabazitaxel :
Cabazitaxel anticancer mechanisms and characteristics of similar to his game dorsey, belongs to the resistance of microtubules.Kappa him through combined with tubulin, promote its assemble into microtubules, at the same time can prevent these has assembled the microtubule disassembly, that stabilize microtubules, thereby inhibiting cell mitosis, and interphase cell function (interphasecellularfunctions).
Application of cabazitaxel:
Cabazitaxel is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
Cabazitaxel is used together with prednisone to treat prostate cancer that has spread to other parts of the body (metastatic).
Cabazitaxel is usually given after other cancer medicines have been tried without success.
Cabazitaxel may also be used for purposes not listed in this medication guide.
What is the most important information I should know about cabazitaxel?
Do not use cabazitaxel if you are pregnant. It could harm the unborn baby.
You should not use cabazitaxel if you have liver disease, low white blood cell counts, or an allergy to any medicine that contains polysorbate 80.
Cabazitaxel can lower blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill. Your blood may need to be tested often.
Cabazitaxel can cause a serious allergic reaction. Call your doctor or tell your caregivers right away if you have a rash or skin redness, chest tightness or trouble breathing, or if you feel like you might pass out.
Cabazitaxel side effects:
Cabazitaxel can cause a serious allergic reaction. Get emergency medical help if you have any of these signs of an allergic reaction: hives, rash or skin redness; chest tightness or trouble breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.
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