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CAS No.71610-00-9 Taxane Drugs Cephalomannine Paclitaxel Related CoMpound A

CAS No.71610-00-9 Taxane Drugs Cephalomannine Paclitaxel Related CoMpound A

  • High Light

    taxane chemotherapy for breast cancer

    ,

    taxane chemotherapy drugs

  • Color
    White Or Off White
  • Appearance
    Crystal Powder
  • Purity
    98%
  • M.F
    C45H53NO14
  • CAS No.
    71610-00-9
  • Other Name
    TAXOL B
  • Place of Origin
    Henan Province, China
  • Brand Name
    U-CHOICE
  • Certification
    ISO 9001 : 2008
  • Model Number
    98%
  • Minimum Order Quantity
    1 kg
  • Price
    Negotiate
  • Packaging Details
    as demand
  • Delivery Time
    3-5 working days
  • Payment Terms
    T/T,
  • Supply Ability
    5000 Kgs Per Month

CAS No.71610-00-9 Taxane Drugs Cephalomannine Paclitaxel Related CoMpound A

Cephalomannine 98% Taxane Drugs CAS No.71610-00-9

 

Chemcial Name:
Paclitaxel Related CoMpound A
(2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7-dihydroxy-13-{[(2R,3S)-2-hydroxy-3-{[(2E)-2-methylbut-2-enoyl]amino}-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah ydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
chephalomannine

Cephalomannine was first discovered in the tree, Cephalotaxus mannii. Since then, it has been discovered in yew trees, Taxus sp., and is commonly eluted with taxol during extract purification.

 

Function of Cephalomannine:
1. With good effect on anti-cancer;
2. With good effect on treating ovarian cancer, breast cancer and lung cancer.

Application of Cephalomannine:
1.It is mainly used in pharmaceutical field;
2.It is mainly used in health product industry;

r at low temperature, keep away from moisture, heat and light.

 

 

Technical Information
Technical Item Technical Data

Density

1.4±0.1 g/cm3

Boiling Point

929.5±65.0 ℃ at 760 mmHg

Molecular Formula

C45H53NO14

Molecular  Weight

831.901

Flash Point

516.0±34.3 ℃

Exact Mass

831.346619

PSA

221.29000

Log P

6.59

Vapour Pressure

0.0± 0.3 mmHg at 25℃

Refractive Index

1.615

 
 
 
 

 

 
 
 
 
 
 
 

 
 
 
 
 

COA Of Cephalomannine

Analysis Specification Result
Appearance White powder Complies
Odor Characteristic Complies
Taste Characteristic Complies
Identification(TLC) ( + ) Positive
Assay (HPLC) 98% Cephalomannine Complies
Sieve analysis NLT 95% pass 80 mesh Complies
Extract solvent Ethanol&Water Complies
Loss on Drying ≤5.0% 2.56%
Residue on Ignition ≤5.0% 2.72%
Heavy Metal <20ppm Complies
As <2ppm Complies
Residual Solvents Eur. Pharm. Complies

 

Microbiology

Analysis Specification Result
Total Plate Count <1000cfu/g 550cfu/g
Yeast & Moulds <100cfu/g 40cfu/g
E.Coli Negative Complies
Salmonella Negative Complies