Cephalomannine 98% Taxane Drugs CAS No.71610-00-9
Technical Item | Technical Data |
---|---|
Density |
1.4±0.1 g/cm3 |
Boiling Point |
929.5±65.0 ℃ at 760 mmHg |
Molecular Formula |
C45H53NO14 |
Molecular Weight |
831.901 |
Flash Point |
516.0±34.3 ℃ |
Exact Mass |
831.346619 |
PSA |
221.29000 |
Log P |
6.59 |
Vapour Pressure |
0.0± 0.3 mmHg at 25℃ |
Refractive Index |
1.615 |
COA Of Cephalomannine
Analysis | Specification | Result |
Appearance | White powder | Complies |
Odor | Characteristic | Complies |
Taste | Characteristic | Complies |
Identification(TLC) | ( + ) | Positive |
Assay (HPLC) | 98% Cephalomannine | Complies |
Sieve analysis | NLT 95% pass 80 mesh | Complies |
Extract solvent | Ethanol&Water | Complies |
Loss on Drying | ≤5.0% | 2.56% |
Residue on Ignition | ≤5.0% | 2.72% |
Heavy Metal | <20ppm | Complies |
As | <2ppm | Complies |
Residual Solvents | Eur. Pharm. | Complies |
Microbiology
Analysis | Specification | Result |
Total Plate Count | <1000cfu/g | 550cfu/g |
Yeast & Moulds | <100cfu/g | 40cfu/g |
E.Coli | Negative | Complies |
Salmonella | Negative | Complies |
Chemcial Name:
Paclitaxel Related CoMpound A
(2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7-dihydroxy-13-{[(2R,3S)-2-hydroxy-3-{[(2E)-2-methylbut-2-enoyl]amino}-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecah ydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
chephalomannine
Cephalomannine was first discovered in the tree, Cephalotaxus mannii. Since then, it has been discovered in yew trees, Taxus sp., and is commonly eluted with taxol during extract purification.
Function of Cephalomannine:
1. With good effect on anti-cancer;
2. With good effect on treating ovarian cancer, breast cancer and lung cancer.
Application of Cephalomannine:
1.It is mainly used in pharmaceutical field;
2.It is mainly used in health product industry;
r at low temperature, keep away from moisture, heat and light.