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Docetaxel USP38 Taxane Drugs For Treatment Of Breast , CAS 114977-28-5

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Docetaxel USP38 Taxane Drugs For Treatment Of Breast , CAS 114977-28-5

Docetaxel USP38 Taxane Drugs For Treatment Of Breast , CAS 114977-28-5
Docetaxel USP38 Taxane Drugs For Treatment Of Breast , CAS 114977-28-5

Large Image :  Docetaxel USP38 Taxane Drugs For Treatment Of Breast , CAS 114977-28-5

Product Details:
Place of Origin: Henan Province, China
Brand Name: U-CHOICE
Certification: ISO 9001 : 2008
Model Number: USP38
Payment & Shipping Terms:
Minimum Order Quantity: 500g
Price: Negotiate
Packaging Details: as demand
Delivery Time: 3-5 working days
Payment Terms: T/T,
Supply Ability: 500 Kgs Per Month
Detailed Product Description
Color: White Or Off White Appearance: Crystal Powder
Standard: USP38 M.F: C43H53NO14
CAS No.: 14977-28-5 UN Number: 1544
HS Code: 2932999099 Other Name: AP-5
High Light:

taxane chemotherapy for breast cancer

,

taxane chemotherapy drugs

Docetaxel USP38 CAS No. 114977-28-5 Taxane Drugs White or off white crystalline powder

 

Technical Information

 

Technical Item Technical Data

Density

1.4±0.1 g/cm3

Boiling Point

900.5±65.0 ℃ at 760 mmHg

Molecular Formula

C43H53NO14

Molecular  Weight

807.879

Flash Point

498.4±34.3 

Exact Mass

807.346619

PSA

224.45000

Log P

6.55

Vapour Pressure

0.0± 0.3 mmHg at 25℃

Refractive Index

1.618

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Docetaxel (trade name Taxotere) is a clinically well established anti-mitotic chemotherapy medication (that is, it interferes with cell division).

 

Function:
Docetaxel is used mainly for the treatment of breast, ovarian, and non-small cell lung cancer.

Docetaxel has an FDA approved claim for treatment of patients who have locally advanced, or metastatic breast or non small-cell lung cancer who have undergone anthracycline-based chemotherapy and failed to stop cancer progression or relapsed. An European approval docetaxel for use in hormone-refractory prostate cancer. Docetaxel is considered better than doxorubicin, paclitaxel and fluorouracil as a cytotoxic antimicrotubule.

1.It is a clinically well established anti-mitotic chemotherapy medication (that is, it interferes with cell division).
2.It is used mainly for the treatment of breast, ovarian, and non-small cell lung cancer.
3.It has an FDA approved claim for treatment of patients who have locally advanced, or metastatic breast or non small-cell lung cancer who have undergone anthracycline based chemotherapy and failed to stop cancer progression or relapsed. An European approval docetaxel for use in hormone-refractory prostate cancer.
4.It is considered better than doxorubicin, paclitaxel and fluorouracil as a cytotoxic antimicrotubule.

 

Application:
Docetaxel intermediate is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever invented. By extracting the pre-cursor, docetaxel intermediate in large quantites from the Taxus baccata leaf, many subsequent semi-syntheses can be carried out.
The esterification of docetaxel intermediate also causes an enhancement in the kinetics, and therefore the pharmacological profile of these important chemo-therapeutic agents.

 

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